University Hospital of Wales

Cardiff, United Kingdom

21 recruiting

Showing 120 of 38 trials

Recruiting
Phase 1Phase 2

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

Acute Leukemia
Janssen Research & Development, LLC420 enrolled103 locationsNCT04811560
Recruiting
Phase 3

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

Carcinoid TumorCarcinoid Tumor of PancreasCarcinoid Tumor of Liver+6 more
Crinetics Pharmaceuticals Inc.141 enrolled51 locationsNCT07087054
Recruiting
Phase 3

MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera

Polycythemia Vera
University of Birmingham586 enrolled47 locationsNCT04116502
Recruiting
Phase 2Phase 3

(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

Indolent Systemic MastocytosisSmoldering Systemic Mastocytosis
Blueprint Medicines Corporation534 enrolled64 locationsNCT04910685
Recruiting
Phase 3

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

Diabetes Mellitus, Type 1
Eli Lilly and Company150 enrolled107 locationsNCT07222137
Recruiting
Phase 2Phase 3

Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

Focal Epilepsy
Biohaven Therapeutics Ltd.390 enrolled174 locationsNCT06309966
Recruiting
Phase 3

A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

Diabetes Mellitus, Type 1
Eli Lilly and Company300 enrolled132 locationsNCT07222332
Recruiting

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

Pulmonary Embolism
Penumbra Inc.1,500 enrolled74 locationsNCT04798261
Recruiting
Phase 3

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Neutropenia
X4 Pharmaceuticals176 enrolled112 locationsNCT06056297
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

Frontotemporal DementiaFTDDementia, Frontotemporal+1 more
AviadoBio Ltd18 enrolled19 locationsNCT06064890
Recruiting
Not Applicable

iCorMicA - Stratified Medicine in Angina

Coronary Artery DiseaseCoronary Microvascular Dysfunction (CMD)Angina, Stable+7 more
NHS Greater Glasgow and Clyde1,500 enrolled39 locationsNCT04674449
Recruiting

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

Aortic Valve Stenosis
The Leeds Teaching Hospitals NHS Trust550 enrolled61 locationsNCT06557798
Recruiting
Not Applicable

Protocolized Reduction of Non-resuscitation Fluids Versus Usual Care in Septic Shock Patients

Septic Shock
Region Skane1,850 enrolled22 locationsNCT06140147
Recruiting
Phase 3

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

Multiple Myeloma
Pfizer944 enrolled238 locationsNCT05020236
Recruiting
Phase 3

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Multiple Myeloma
Kite, A Gilead Company450 enrolled124 locationsNCT06413498
Recruiting
Phase 2

A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease

Chronic Graft Versus Host Disease
Incyte Corporation120 enrolled70 locationsNCT06388564
Recruiting
Phase 3

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

Multiple Myeloma
Janssen Research & Development, LLC795 enrolled242 locationsNCT06208150
Recruiting
Phase 3

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.160 enrolled138 locationsNCT05667142
Recruiting

A Global Prospective Observational Registry of Patients With Pompe Disease

Pompe Disease
Amicus Therapeutics500 enrolled41 locationsNCT06121011
Recruiting
Not Applicable

Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers

Differentiated Thyroid Cancer
University College, London456 enrolled33 locationsNCT05604963