University Hospital of Wales

Cardiff, United Kingdom

21 recruiting

Showing 120 of 46 trials

Recruiting
Phase 3

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

Acute Myeloid Leukemia, Adult
Stichting Hemato-Oncologie voor Volwassenen Nederland448 enrolled201 locationsNCT06652438
Recruiting
Phase 1Phase 2

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

Acute Leukemia
Janssen Research & Development, LLC420 enrolled102 locationsNCT04811560
Recruiting
Phase 2

Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

Multiple Myeloma in RelapseMultiple Myeloma, Refractory
CellCentric Ltd.100 enrolled30 locationsNCT07096778
Recruiting
Phase 3

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

Diabetes Mellitus, Type 1
Eli Lilly and Company150 enrolled110 locationsNCT07222137
Recruiting
Phase 2

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)

Progressive Multiple Sclerosis
Hoffmann-La Roche360 enrolled103 locationsNCT07282574
Recruiting
Phase 3

A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

Diabetes Mellitus, Type 1
Eli Lilly and Company300 enrolled136 locationsNCT07222332
Recruiting
Phase 3

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Multiple Myeloma
Pfizer1,116 enrolled127 locationsNCT05623020
Recruiting

Registry for Patients With X-Linked Hypophosphatemia

X-linked Hypophosphatemia
Kyowa Kirin Pharmaceutical Development Ltd1,489 enrolled118 locationsNCT03193476
Recruiting
Phase 3

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.160 enrolled138 locationsNCT05667142
Recruiting

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

Pulmonary Embolism
Penumbra Inc.1,500 enrolled79 locationsNCT04798261
Recruiting
Phase 2

Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind, Placebo-controlled, Multi-centre Trial (RAPID-I)

Acute Pancreatitis
University of Liverpool240 enrolled14 locationsNCT03684278
Recruiting
Phase 1Phase 2

A Study Assessing HMB-002 in Participants With Von Willebrand Disease

Von Willebrand Disease (vWD)Von Willebrand Disease (VWD), Type 2Von Willebrand Disease (VWD), Type 1+1 more
Hemab ApS108 enrolled25 locationsNCT06754852
Recruiting
Phase 3

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

Carcinoid TumorCarcinoid Tumor of PancreasCarcinoid Tumor of Liver+6 more
Crinetics Pharmaceuticals Inc.141 enrolled51 locationsNCT07087054
Recruiting
Phase 2Phase 3

(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

Indolent Systemic MastocytosisSmoldering Systemic Mastocytosis
Blueprint Medicines Corporation534 enrolled71 locationsNCT04910685
Recruiting

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

Aortic Valve Stenosis
The Leeds Teaching Hospitals NHS Trust550 enrolled71 locationsNCT06557798
Recruiting
Phase 1Phase 2

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

Acute Myeloid LeukemiaNon-Hodgkin LymphomaMultiple Myeloma+3 more
CellCentric Ltd.250 enrolled39 locationsNCT04068597
Recruiting
Phase 2

A Phase 2 Study to Assess STP938 (Dencatistat) as a Monotherapy in Adults With High Risk Essential Thrombocythaemia - The VECTRA Trial

Essential Thrombocythaemia
Step Pharma, SAS50 enrolled14 locationsNCT06786234
Recruiting
Not Applicable

RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

Heart Failure
University Hospital Southampton NHS Foundation Trust2,504 enrolled47 locationsNCT05568069
Recruiting
Phase 2

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

InfectionsAcute Respiratory Distress Syndrome
BioAegis Therapeutics Inc.600 enrolled70 locationsNCT05947955
Recruiting

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb1,700 enrolled99 locationsNCT05489705