Clinical Trials in London, London

62 recruiting

Showing 120 of 48 trials

Recruiting

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Intensive Care MedicineOpioid analgesiaExtracorporeal Membrane Oxygenation (ECMO)+5 more
Guy's and St Thomas' NHS Foundation Trust120 enrolled1 locationNCT07032987
Recruiting
Not Applicable

Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial

Skin healthRosaceaMenopause+5 more
King's College London30 enrolled1 locationNCT07341087
Recruiting

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

Geographic Atrophy secondary to Age Related Macular Degeneration
Complement Therapeutics75 enrolled9 locationsNCT07144137
Recruiting
Phase 3

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

Niemann-Pick Type C Disease
Azafaros A.G.72 enrolled34 locationsNCT07082725
Recruiting
Phase 3

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

GM1 GangliosidosisGM2 GangliosidosisNiemann-Pick Type C Disease
Azafaros A.G.147 enrolled37 locationsNCT07054515
Recruiting
Phase 2

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc.140 enrolled42 locationsNCT04996875
Recruiting

The Physiotherapy Assessment of Breathing Pattern Disorder

BreathlessnessBreathing Pattern Disorder
Royal Brompton & Harefield NHS Foundation Trust150 enrolled1 locationNCT07543588
Recruiting
Phase 2

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary FibrosisInterstitial Lung DiseasePulmonary Fibrosis+7 more
Avalyn Pharma Inc.375 enrolled152 locationsNCT06329401
Recruiting

The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN)

Sarcoma,Soft TissueEpithelioid Hemangioendothelioma
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano100 enrolled22 locationsNCT06408441
Recruiting
Not Applicable

BEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear Implants

Hearing LossDeafnessHearing Loss, Sensorineural+1 more
Guy's and St Thomas' NHS Foundation Trust272 enrolled13 locationsNCT05808543
Recruiting
Phase 4

The STOP-MED CTRCD Trial

Heart FailureCancerCardiotoxicity+2 more
Dinesh Thavendiranathan335 enrolled14 locationsNCT06183437
Recruiting
Phase 3

A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2)

Chronic Hepatitis D Infection
Mirum Pharmaceuticals, Inc.172 enrolled44 locationsNCT07200908
Recruiting
Phase 1Phase 2

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

Metastatic Breast CancerHormone Receptor-Positive Breast CancerHormone Receptor Positive HER-2 Negative Breast Cancer
Ellipses Pharma95 enrolled14 locationsNCT05573126
Recruiting
Phase 3

Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults

Traumatic Brain Injury
London School of Hygiene and Tropical Medicine5,000 enrolled2 locationsNCT04521881
Recruiting
Phase 2

A Trial of "APL-9796'' in Adults With Pulmonary Hypertension

Pulmonary Arterial Hypertension
Apollo Therapeutics Ltd48 enrolled5 locationsNCT06846554
Recruiting
Not Applicable

RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

Heart Failure
University Hospital Southampton NHS Foundation Trust2,504 enrolled47 locationsNCT05568069
Recruiting
Phase 3

A Study Investigating Coagadex in the Treatment AFXD Associated With AL Amyloidosis

Acquired Factor X Deficiency
Kedrion S.p.A.15 enrolled3 locationsNCT06963216
Recruiting

Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib

Alopecia Areata
Pfizer850 enrolled58 locationsNCT06531109
Recruiting
Not Applicable

Dance/Movement Therapy for Functional Neurological Disorder

Functional neurological disorder
King's College London30 enrolled1 locationNCT07378488
Recruiting
Phase 3

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER).

Eye DiseasesMacular Degeneration, WetSub-Macular Hemorrhage
King's College Hospital NHS Trust210 enrolled36 locationsNCT04663750