Does early whooping cough (pertussis) vaccination provide earlier antibody protection for infants?
Does early whooping cough (pertussis) vaccination provide earlier antibody protection for infants? A pilot study to determine the appropriate design for a trial of acellular pertussis vaccine given at birth?
National Centre for Immunisation Research and Surveillance
80 participants
Apr 11, 2005
Interventional
Conditions
Summary
In this study the antibody response (immunity) to pertussis vaccination will be compared in 3 groups, those who have routine pertussis vaccination commmencing at 2 months old with those who have received pertussis vaccines at birth and 1 month old or only birth.
Eligibility
Inclusion Criteria1
- Healthy Newborns less than 5 days old and born after 37 weeks gestation
Exclusion Criteria1
- Serious chronic illness or immunodeficiency
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Interventions
Group 1 - pertussis vaccination at birth and 1 month old followed by routine vaccination Group 2 - pertussis vaccination at birth followed by routine vaccination
Locations(1)
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ACTRN12605000013662