G-CSF for the prevention of mortality from severe melioidosis in Ubon Ratchathani, Thailand

This study looks at whether a treatment called G-CSF (a medication that boosts white blood cells) can help people with a severe bacterial infection called melioidosis survive. Melioidosis is a serious infection more common in parts of Asia and Northern Australia. The study is being conducted in Thailand. You may be eligible if: - You are 14 years of age or older - You have been diagnosed with or are suspected to have melioidosis causing severe sepsis (serious infection with organ dysfunction) You may NOT be eligible if: - You are under 14 years old - You are pregnant - You have an allergy to the study drugs - You have a blood cancer (haematological malignancy) - You have a very low white blood cell count due to cancer treatment (febrile neutropenia) Talk to your doctor about whether this trial might be right for you.