RecruitingPhase 3ACTRN12605000082606

INSTEP Trial

Influence of NSAID on Short Term Efficacy of Pleurodesis for recurrent pneumothorax


Sponsor

Gavin M Wright

Enrollment

100 participants

Start Date

Dec 15, 2004

Study Type

Interventional

Conditions

Summary

For pain relief after VATS pleurodesis, patients are given either Celebrex or Placebo for 5 days plus any other required analgesics. We aim to determine whether there is any difference in failure of the lung to adhere to the lining of the chest.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Inclusion Criteria1

  • Patients with surgical indication for pleurodesis due to recurrent or persistent pneumohtorax

Exclusion Criteria2

  • Chronic NSAID usage that cannot be stopped for more than 24 hours prior to surgery.
  • Renal impairment

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Interventions

Celebrex 200mg bd 5 days

Celebrex 200mg bd 5 days


Locations(1)

St Vincent's Hospital (Melbourne) Ltd - Fitzroy

VIC, Australia

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ACTRN12605000082606