RecruitingACTRN12605000128695

Improved characterisation of the clinical phenotype of Hereditary Motor Sensory Neuropathy of neuronal type with onset of symptoms in early childhood, especially with respect to disease progression with age and the incidence of such complications as foot deformity, contractures, scoliosis and respiratory involvement - an observational study.


Sponsor

The Children's Hospital at Westmead

Enrollment

20 participants

Start Date

Feb 1, 2004

Study Type

Observational

Conditions


Eligibility

Sex: Both males and females

Inclusion Criteria1

  • Subjects will have a diagnosis of HMSN of neuronal type with onset in early childhood, based upon their clinical findings and family history, neurophysiological assessments and, where applicable, pathological testing (nerve and muscle biopsies).

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Interventions

This study primarily constitutes a review of a well-defined cohort of patients. The interventions planned include clinical examination and quantitative strength testing, a hip X-ray, neurophysiology t

This study primarily constitutes a review of a well-defined cohort of patients. The interventions planned include clinical examination and quantitative strength testing, a hip X-ray, neurophysiology testing, and blood sampling for genetic testing.


Locations(1)

Australia

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ACTRN12605000128695