RecruitingPhase 2Phase 3ACTRN12605000133639

The effect of heparin on lung function following cardiopulmonary bypass.

The effect of heparin on alveolar dead space following cardiopulmonary bypass.

Sponsor

Nil

Enrollment

30 participants

Start Date

Nov 30, 2004

Study Type

Interventional

Conditions

Lung injury following cardiac surgery.

Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study looks at whether a specific dose of heparin (a blood-thinning medication commonly used during heart surgery) affects how well the lungs work after coronary artery bypass graft (CABG) surgery. Heart-lung bypass machines can sometimes cause temporary lung inflammation, and researchers want to know if heparin dosing makes a difference. You may be eligible if: - You are an adult (18 years or older) - You are scheduled for planned coronary artery bypass graft (heart bypass) surgery using a heart-lung bypass machine You may NOT be eligible if: - You have had a previous bad reaction to heparin - You are currently bleeding - You are having an additional surgical procedure beyond the heart bypass - Your kidney function is significantly impaired (creatinine above 200 umol/L) Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

A double blind randomised trial comparing intravenous heparin versus placebo (5% glucose). The infusion will be commenced 8 - 10 hours prior to commencement of surgery and ceased prior to the inserti

A double blind randomised trial comparing intravenous heparin versus placebo (5% glucose). The infusion will be commenced 8 - 10 hours prior to commencement of surgery and ceased prior to the insertion of lines or sternotomy.

Locations(1)

Australia

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ACTRN12605000133639