The GABA Study
Single-dose Pregabalin in Postoperative Pain Relief after Minor Gynaecological Surgery
Professor Michael Paech
90 participants
Aug 8, 2005
Interventional
Conditions
Summary
Women undergoing D&C surgery often experience pain afterwards between 2 and 7 on a scale of 1-10. This pain is intially due to surgical trauma but may continue because of resulting inflammation. If the ongoing cycle of inflammation is reduced pain may be less. Pregabalin is a treatment for seizure disorders. It also has pain relieving and calming properties. It can reduce local tissue inflammation and the release of pain mediators. Therefore pregabalin given preoperatively may reduce postoperative pain.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Single-dose pregabalin 100 mg administered 1-2 hours pre-operatively, effect on postoperative pain assessed.
Locations(1)
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ACTRN12605000223639