Long term use of azithromycin for chronic lung disease in Aboriginal adults: a randomised controlled trial.

This study is testing whether taking the antibiotic azithromycin once a week for one year can reduce chest infections in Aboriginal adults with a lung disease called COPD (chronic obstructive pulmonary disease). COPD makes it hard to breathe, and people with this condition often get repeated chest infections that damage the lungs further. Researchers want to see if this weekly antibiotic can reduce how often and how badly these infections happen. You may be eligible if: - You are an Indigenous Australian adult (18 years or older) - You have COPD confirmed by breathing tests - You have had a chronic cough and phlegm most days for more than one year - You are able to give your agreement to take part You may NOT be eligible if: - You are pregnant, planning to become pregnant, or are breastfeeding - You are already taking long-term antibiotics - You are allergic to macrolide antibiotics - You have bronchiectasis (a specific type of lung damage visible on X-ray) - You have a serious heart or kidney disease - You are already taking part in another antibiotic or vaccine study - You are unlikely to be available for the full duration of the trial Talk to your doctor about whether this trial might be right for you.