CompletedPhase 2ACTRN12605000237684

Phase II Study of AVAC (TM) for the Treatment of Atopic Dermatitis in Children

A blinded, randomised, placebo-controlled Phase II study to evaluate the safety and efficacy of 12.5 mcg AVAC (TM) (delipidated, deglycolipidated and arabinogalactan depleted derivative of heat-killed Mycobacterium vaccae suspension) in children with moderate-to-severe atopic dermatitis (AD)


Sponsor

Genesis Research & Development Corporation Ltd

Enrollment

120 participants

Start Date

Oct 7, 2003

Study Type

Interventional

Conditions


Eligibility

Sex: Both males and femalesMin Age: 5 YearssMax Age: 18 Yearss

Inclusion Criteria1

  • Diagnosis of moderate-to-severe atopic dermatitis (AD). Severity defined according to Rajka and Langeland criteria; atopic dermatitis defined according to UK Atopic Dermatitis Working Party criteria.

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Interventions

3 intradermal injections of AVAC (TM) at intervals of 2 weeks (Weeks 0, 2 and 4)

3 intradermal injections of AVAC (TM) at intervals of 2 weeks (Weeks 0, 2 and 4)


Locations(1)

New Zealand

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ACTRN12605000237684