RecruitingPhase 4ACTRN12605000273684

A comparison of topical anaesthesia with placebo for the managment of minor corneal trauma.

Topical anaesthesia (does / does not) delay re-epithelialisation after minor corneal trauma.


Sponsor

Ken Barns

Start Date

May 2, 2006

Study Type

Interventional

Conditions

Summary

A pilot study to investigate the safety of using local anaesthetic eye drops to control pain following minor corneal injuries.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Inclusion Criteria1

  • (a) Superficial corneal abrasion with clear history of trauma; (b) superficial corneal abrasion with foreign body; or (c) ultraviolet keratitis with clear history of welding flash exposure.

Exclusion Criteria1

  • (a) 36hr or more since event causing the corneal injury; (b) aged under 18yr; (c) history of any of - unacceptable adverse reaction to any local anaesthetic agent or to any ophthalmic preparation, visual impairment secondary to another eye pathology other than simple refractive error, contact lens use, previous participation in this trial, or current pregnancy/lactation; (d) signs of conjunctival infection; (e) functionally one-eyed; or (f) patient requiring referral for ophthalmological opinion.

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Interventions

Dispensing 1.5 mL of eye drops, 0.4% amethocaine, for out-patient management of ocular pain in the first 48hr following the initial emergency department presentation with corneal abrasion, corneal for

Dispensing 1.5 mL of eye drops, 0.4% amethocaine, for out-patient management of ocular pain in the first 48hr following the initial emergency department presentation with corneal abrasion, corneal foreign body or UV keratitis.


Locations(1)

Australia

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ACTRN12605000273684