The Duration of Action of Zoledronate study

This clinical trial is studying the Duration of Action of Zoledronate study. You may be eligible if you are women aged 18 and older who postmenopausal 5 yrs or more, bone density T score between -1.0 and -2.0 at lumbar spine or total hip. People with renal impairment (serum creatinine >0.15 mmol/l), chronic liver disease, untreated hypothyroidism or hyperthyroidism may not be able to participate. Participation may involve medical tests, study visits, and follow-up appointments.