RecruitingPhase 3ACTRN12605000347662

Continuous infusion of local anaesthetic in the control of pain following colorectal surgery


Sponsor

Mazda Foundation - Private Bag 40, Mount Waverley BC, Vic 3149

Enrollment

300 participants

Start Date

Dec 6, 2004

Study Type

Interventional

Conditions

Summary

To determine if there is a better and safer option for pain relief following laparotomies for colorectal surgery, by using a continuous infusion of local anaesthetic into the wound.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study is testing a pain relief method where local anaesthetic is continuously delivered directly into a surgical wound after bowel surgery through a small tube. Surgeries on the large bowel (colon or rectum) often cause significant pain, and this new method aims to be a better alternative to morphine pumps or epidurals. Researchers want to find out if this technique provides good pain relief and reduces the need for stronger opioid medications. You may be eligible if: - You are 18 years of age or older - You are having open bowel surgery (colorectal surgery) - You are able to give written consent You may NOT be eligible if: - You are allergic to lignocaine or ropivacaine (local anaesthetics) - You have a true allergy to morphine - You are having an epidural or spinal infusion - You are having emergency surgery - You have cognitive impairment or a history of altered mental state Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

To determine whether continous local anaesthetic, ie. ropivacaine 1% (Naropin - produced by AstroZeneca) via a dual catheter PainBuster Soaker Pain Management System (produced by I-Flow) is a more eff

To determine whether continous local anaesthetic, ie. ropivacaine 1% (Naropin - produced by AstroZeneca) via a dual catheter PainBuster Soaker Pain Management System (produced by I-Flow) is a more effective form of post operative analgesia compared to traditional analgesias for midline incisions following major colorectal resections. The PainBuster Soaker System is tested in a randomised double blinded control study where participants either receive ropivacaine 1% or Saline in their PainBuster Device for the first three days. Both groups also receive a Morphine PCA, Tramadol, Ketorolac and Panadol.


Locations(1)

Australia

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ACTRN12605000347662