Use of ethanol to prevent infection in tunnelled intravenous catheters in haematology patients treated with chemotherapy.

This study is testing whether flushing a central venous catheter (a tube inserted into a large vein) with ethanol (alcohol) can help prevent serious infections in patients with blood cancer who are receiving chemotherapy. Central line infections can be life-threatening in these vulnerable patients. Researchers want to find out if regular alcohol flushes can kill bacteria and reduce infection rates. You may be eligible if: - You are 18 years of age or older - You have a haematological malignancy (blood cancer) or are having a bone marrow transplant - You have a central venous catheter in place - You are admitted to hospital for chemotherapy that requires a stay of more than 5 days - You are willing and able to give consent You may NOT be eligible if: - You are allergic to ethanol (alcohol) - You are receiving chemotherapy as an outpatient - You have had a positive blood culture from your central line in the last 7 days - Your liver function tests are significantly elevated - You have a known history of alcoholism - You are pregnant or breastfeeding - You have a fever above 38°C at the time of enrolment Talk to your doctor about whether this trial might be right for you.