CompletedPhase 2ACTRN12605000432617

Multi-Center, Phase Ib/IIa Safety and Preliminary Efficacy Study of Phenoxodiol (Intravenous Dosage Form and Oral Dosage Form) as a Chemo-Sensitizing Agent for Cisplatin, Carboplatin and Paclitaxel in Epithelial Ovarian Cancer or Primary Peritoneal Cancer that is Platinum- and/or Taxane-Refractory or Resistant.


Sponsor

Marshall Edwards Pty Ltd

Enrollment

100 participants

Start Date

Apr 7, 2004

Study Type

Interventional

Conditions


Eligibility

Sex: FemalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This early-phase trial tests the safety of Phenoxodiol, given both intravenously and orally, in women with advanced ovarian, fallopian tube, or peritoneal cancer that has not responded to standard chemotherapy. Women aged 18 and older who have already tried other treatments may be eligible. Participation involves receiving the study drug and regular monitoring.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Phenoxodiol intravenous and oral dosage formulations in combination with cisplatin, carboplatin or paclitaxel. The duration is for a maximum of 8 x 6 week treatment cycles (48 weeks).

Phenoxodiol intravenous and oral dosage formulations in combination with cisplatin, carboplatin or paclitaxel. The duration is for a maximum of 8 x 6 week treatment cycles (48 weeks).


Locations(1)

Australia

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ACTRN12605000432617