RecruitingACTRN12605000441617

Use of a CO2 clamp and or CPAP to stabilize respiration in patients with combined central and obstructive sleep apnoea


Sponsor

Dr R Ratnavadivel, Adelaide Institute for Sleep Health, Daws Rd, Daw Park SA 5041

Enrollment

10 participants

Start Date

Mar 1, 2005

Study Type

Interventional

Conditions


Eligibility

Sex: Both males and females

Plain Language Summary

Simplified for easier understanding

This study is looking at two treatments to help people who stop breathing during sleep — a problem called sleep apnoea. Some people have both central sleep apnoea (where the brain doesn't send the right signals to breathe) and obstructive sleep apnoea (where the airway is blocked). Researchers are testing whether using extra carbon dioxide (CO2) and a breathing device called CPAP can help stabilize breathing during sleep. You may be eligible if: - You have been diagnosed with central and/or obstructive sleep apnoea - Your condition has been stable for at least the past month - You are willing and able to give informed consent You may NOT be eligible if: - You have a significant psychiatric (mental health) condition - You have claustrophobia (fear of enclosed spaces) - You are unable to tolerate wearing a CPAP mask overnight Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

To test efficacy of device under development in treating combined central and obstructive sleep apnoea as compared to conventional CPAP as control. The subject will undergo one night polysomnography

To test efficacy of device under development in treating combined central and obstructive sleep apnoea as compared to conventional CPAP as control. The subject will undergo one night polysomnography whilst using device and one night polysomnography with CPAP (control) in randomized order 1 week apart. The subject will be requested to wear CPAP at night for one week at home prior to each study night to acclimatize to positive airway pressure and mask.


Locations(1)

Australia

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ACTRN12605000441617