RecruitingACTRN12605000445673

Protein turnover and energy expenditure in normal subjects, growth hormone deficiency, acromegaly and Cushing's syndrome

Comparison of protein turnover and energy expenditure in growth hormone deficiency, acromegaly and Cushing's syndrome before and after surgery to normal subjects


Sponsor

St Vincent's Hospital

Enrollment

80 participants

Start Date

Jan 1, 1995

Study Type

Observational

Conditions

Summary

Acromegaly, GH deficiency and Cushing's syndrome all alter body protein. The aim was to compare protein metabolism in these 3 conditions to normal subjects, along with how protein metabolism changes following surgical removal of hormone-secreting tumour.


Eligibility

Sex: Both males and females

Inclusion Criteria1

  • Subjects with GH deficiency, acromegaly and Cushing's syndrome and normal volunteers.

Exclusion Criteria1

  • Cancer, hepatic and renal failure.

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Interventions

Resection of hormone secreting tumour in subjects with acromegaly and Cushing's syndrome only. the study involves observation of people who have undergone surgery as part of their routine medical care

Resection of hormone secreting tumour in subjects with acromegaly and Cushing's syndrome only. the study involves observation of people who have undergone surgery as part of their routine medical care.


Locations(1)

Australia

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