RecruitingPhase 2ACTRN12605000454673

Does the use of nizatidine (Tazac) as a prokinetic agent improve gastric emptying in patients who have had an oesophagectomy for oesophageal cancer?


Sponsor

Cabrini Clinical Education and Research Institute

Enrollment

20 participants

Start Date

Dec 1, 2004

Study Type

Interventional

Conditions

Summary

The purpose of this project is to see whether nizatidine, a drug commonly used to treat peptic ulcers and reflux disease, may improve the emptying of the stomach in patients who have had an operation for oesophageal cancer. Participation in this project involves taking the trial medication for one week and having a special gastric empyting scan before and after one week of treatment with the drug. The scan involves a small dose of radiation which has been approved by the Department of Human Services, Radiation Safety Approval.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study looks at whether a medication called nizatidine (brand name Tazac), which is normally used to treat stomach ulcers and acid reflux, can also help the stomach empty food more efficiently in people who have had surgery to remove the oesophagus (the tube connecting your throat to your stomach) because of cancer. After this surgery, many patients experience slow stomach emptying, which causes discomfort. Participants take the medication for one week and have a special stomach scan before and after to measure any changes. You may be eligible if: - You are 18 years or older - You have had an oesophagectomy (oesophagus removal surgery) at least 6 months ago - You are able to give written consent You may NOT be eligible if: - You are allergic to nizatidine - You are currently undergoing further treatment for oesophageal cancer - You are mentally or legally unable to give consent - You are pregnant or may be pregnant Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Australia

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ACTRN12605000454673