Heparin In Total Parenteral Nutrition
Randomised controlled trial of heparin in total parenteral nutrition to reduce the complications of peripherally inserted central venous catheters (long lines) in neonates.
Dr Pita Birch
200 participants
Mar 5, 2004
Interventional
Conditions
Summary
In this trial we are testing the hypothesis that the addition of low dose heparin to total parenteral nutrition reduces the complications associated with long lines in neonates, particularly long line infections. We are investigating the possible benefits of heparin in improving the delivery of TPN to sick or premature neonates. In this study half of the babies will have heparin added to their TPN and the other half will have TPN without heparin. No one, except for the pharmacists, will know which babies are having heparin and which ones are not and this makes the trial double blind. At the end of the study we will compare the two groups to see if the babies that have had heparin have had less infections or less complications in general.
Eligibility
Plain Language Summary
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Interventions
Randomised double blind controlled trial with Heparin added to the total parenteral nutrition at a concentration of 0.5IU/mL. The intervention continues for as long as the infant is receiving total parenteral nutrition or a predetermined end site is reached, such as confirmed central line infection.
Locations(1)
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ACTRN12605000579695