RecruitingPhase 3ACTRN12605000581662

PRACTICAL TRIAL

Platelet Responsiveness to Aspirin and Clopidogrel and Troponin Increase after Coronary intervention in Acute coronary Lesions


Sponsor

Cardiology Dept, Royal Perth Hospital

Enrollment

370 participants

Start Date

Jan 1, 2004

Study Type

Interventional

Conditions

Summary

A multi-centre, randomised, double-blind, clinical trial comparing a 600mg versus 300mg loading dose of Clopidogrel on the Incidence of Myonecrosis and Laboratory Measures of Platelet Inhibition following early Percutaneous Coronary Intervention in Acute Coronary Syndrome patients.


Eligibility

Sex: Both males and females

Inclusion Criteria1

  • abnormal electrocardiogram 2. evidence of myonecrosis (elevated troponin I or T above ULN) at presentation.3. known coronary artery disease with previous MI, PCI, CABG surgery, or positive stress test.

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Interventions

Clopidogrel Loading Dose 300mg vs 600mg

Clopidogrel Loading Dose 300mg vs 600mg


Locations(1)

Australia

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