ActivePhase 2Phase 3ACTRN12605000633684

Trial of an experimental soft contact lens designed to inhibit the progression of axial myopia in children.

Trial of an experimental frequent-replacement soft contact lens designed to correct vision and simultaneously produce myopic retinal defocus during distance and near vision in order to inhibit axial elongation of the eye and myopia progression in children.


Sponsor

Dr John Phillips, Senior Lecturer, Department of Optometry, University of Auckland

Enrollment

40 participants

Start Date

Nov 1, 2005

Study Type

Interventional

Conditions


Eligibility

Sex: Both males and femalesMin Age: 11 YearssMax Age: 14 Yearss

Inclusion Criteria1

  • Progressing myopia, spherical equivalent refraction of -1.50 to -4.00, visual acuity of 6/6 or better, ability to independently handle contact lenses, prepared to wear contact lenses full-time for the duration of the study.

Exclusion Criteria1

  • Astigmatism > 0.75D, anisometropia > 1.00D, abnormal binocular vision, ocular pathology, systemic disease with ocular complications, active anterior surface disease that would preclude contact lens wear, inadequate fit of soft contact lenses.

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Interventions

A frequent replacement soft contact lens that both corrects vision and simultaneously produces myopic retinal defocus will be worn monocularly for 10 months by children with progressing myopia. The fe

A frequent replacement soft contact lens that both corrects vision and simultaneously produces myopic retinal defocus will be worn monocularly for 10 months by children with progressing myopia. The fellow eye will be corrected with a standard single vision frequent replacement soft contact lens. At cross-over (after 10 months) the identity of the eyes wearing the experimental and the single vision lenses will be reversed and the lenses will be worn for a further 10 months.


Locations(1)

New Zealand

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ACTRN12605000633684