CompletedPhase 3Phase 4ACTRN12605000640606

Milrinone for Free Flap Surgery

Milrinone versus placebo infusion intraoperatively to prevent vasospasm during free flap surgery


Sponsor

Department of Anaesthesia, St Vincent's Hospital Melbourne

Enrollment

100 participants

Start Date

May 1, 2002

Study Type

Interventional

Conditions


Eligibility

Sex: Both males and females

Plain Language Summary

Simplified for easier understanding

This study tests whether a medication called milrinone can help improve blood flow during free flap surgery, a procedure where tissue is moved from one part of the body to another. Both men and women who are scheduled for elective free flap surgery may be eligible. Participants would receive either milrinone or a comparison treatment during their surgery.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Double-blind, randomised control trial comparing free flap surgery outcomes after intra-operative Milrinone or placebo at 0.25ug/kg/min infusion during anaesthesia with a 25ug/kg bolus over 20 minutes

Double-blind, randomised control trial comparing free flap surgery outcomes after intra-operative Milrinone or placebo at 0.25ug/kg/min infusion during anaesthesia with a 25ug/kg bolus over 20 minutes after induction of anaesthesia.


Locations(1)

Australia

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ACTRN12605000640606