Treatment of glucocorticoid-induced protein wasting

This study is looking at whether growth hormone and testosterone-like medicines can help reduce the muscle weakness and skin thinning that often happens when people take steroid medicines (like prednisone) for a long time. Long-term steroid use is sometimes needed for conditions like rheumatoid arthritis or polymyalgia rheumatica, but it can cause the body to lose protein, leading to weaker muscles and thinner skin. This trial tests whether these treatments can protect the body from that protein loss. You may be eligible if: - You have been taking prednisone for more than 6 months - You are taking prednisone for polymyalgia rheumatica or inflammatory arthritis You may NOT be eligible if: - You have diabetes mellitus - You have been diagnosed with cancer - You have liver failure - You have kidney failure Talk to your doctor about whether this trial might be right for you.