Amisulpride Naturalistic Study

This study is testing a medicine called amisulpride for people diagnosed with schizophrenia or schizoaffective disorder. Amisulpride is an 'atypical' antipsychotic, which means it is a newer type of medication that may have fewer side effects than older antipsychotics. The study lasts 24 weeks and will look at how safe and effective amisulpride is, how it affects quality of life, and how it impacts thinking and memory. You may be eligible if: - You are between 18 and 65 years old - You have been diagnosed with schizophrenia (any type) or schizoaffective disorder - Your doctor thinks it is appropriate for you to try amisulpride — for example, because your current medication is not working well or causing side effects, or you have just been diagnosed You may NOT be eligible if: - You have a different primary psychiatric diagnosis (other than schizophrenia or schizoaffective disorder) - You are known to be allergic or sensitive to amisulpride - You have had Neuroleptic Malignant Syndrome (a serious reaction to antipsychotic medicines) - You have a significant abnormal ECG (heart tracing) - You were previously taking clozapine for treatment-resistant psychosis - You have not had a response problem with your current antipsychotic and do not need a switch Talk to your doctor about whether this trial might be right for you.