CompletedPhase 3ACTRN12605000712606

Adjuvant GIST Trial

Intermediate and high risk localised, completely resected, gastrointestinal stromal tumours (GIST) expressing KIT recepto: a controlled randomised trial on adjuvant Imatinib mesylate (Glivec) versus no further therapy after complete surgery


Sponsor

AGITG

Enrollment

400 participants

Start Date

Oct 20, 2008

Study Type

Interventional

Conditions


Eligibility

Sex: Both males and females

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Adjuvant GIST Trial. It is looking for adults who may be eligible to participate. Participants may need to meet certain health requirements, including: histologically proven diagnosis of GIST (positive for CD117), intermediate or high risk of relapse documented on surgical specimen, surgery performed between 2 weeks and 3 months before treatment start , non evidence of residual macroscopic disease after surgery (R0 or R1 resection only), no prior treatment for GIST (ie. radiotherapy, chemotherapy, molecular targeted therapy, biological therapy), absence of distant metastases, WHO performance status 0.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Imatinib mesylate (400mg/day) for two years

Imatinib mesylate (400mg/day) for two years


Locations(1)

NSW,QLD,SA,TAS,WA,VIC, Australia

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ACTRN12605000712606