CompletedPhase 3ACTRN12605000712606
Adjuvant GIST Trial
Intermediate and high risk localised, completely resected, gastrointestinal stromal tumours (GIST) expressing KIT recepto: a controlled randomised trial on adjuvant Imatinib mesylate (Glivec) versus no further therapy after complete surgery
Sponsor
AGITG
Enrollment
400 participants
Start Date
Oct 20, 2008
Study Type
Interventional
Conditions
Eligibility
Sex: Both males and females
Plain Language Summary
Simplified for easier understanding
This clinical trial is studying Adjuvant GIST Trial. It is looking for adults who may be eligible to participate. Participants may need to meet certain health requirements, including: histologically proven diagnosis of GIST (positive for CD117), intermediate or high risk of relapse documented on surgical specimen, surgery performed between 2 weeks and 3 months before treatment start , non evidence of residual macroscopic disease after surgery (R0 or R1 resection only), no prior treatment for GIST (ie. radiotherapy, chemotherapy, molecular targeted therapy, biological therapy), absence of distant metastases, WHO performance status 0.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Imatinib mesylate (400mg/day) for two years
Imatinib mesylate (400mg/day) for two years
Locations(1)
View Full Details on ANZCTR
For the most up-to-date information, visit the official listing.
ACTRN12605000712606