RecruitingACTRN12605000796684

Effect of TIVA versus Sevoflurane on the incidence of post operative nausea and vomiting following day case gynaecology surgery


Sponsor

Hayden White

Enrollment

130 participants

Start Date

Nov 1, 2006

Study Type

Interventional

Conditions

Summary

Rational for project Many studies have investigated the treatment of post operative nausea and vomiting (PONV) However, there is disagreement on both the incidence of PONV and how to prevent it Few studies have investigated the period post discharge Day case gynaecological surgery patients are particularly at risk of PONV There is evidence that total intravenous anaethesia may decrease the incidence of PONV This study sets out to investigate a specific subgroup of high risk patients. This will allow for specific recommendations to be made regarding the management of this subgroup of patients.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study is looking at two different types of general anaesthesia for day-case (outpatient) gynaecological surgery — TIVA (total intravenous anaesthesia, where all medicines are given through a drip) versus sevoflurane (a gas inhaled to keep patients asleep). The study focuses on which method causes less post-operative nausea and vomiting (PONV), especially after the patient goes home, as nausea after surgery is very uncomfortable and a common reason for unplanned hospital stays. You may be eligible if: - You are 18 years or older - You are a woman having day-case gynaecological surgery under general anaesthesia You may NOT be eligible if: - You are classified as high anaesthetic risk (ASA IV or V) - You have allergies to the study medications - You are pregnant or breastfeeding - You have a psychiatric illness - You are having an epidural as part of your anaesthesia - You are planned to stay overnight in hospital Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Total intravenous anaesthetic. Prospective randomised trial. Patients stratified into high and low risk. The trial is to run over approximately 12 months.

Total intravenous anaesthetic. Prospective randomised trial. Patients stratified into high and low risk. The trial is to run over approximately 12 months.


Locations(1)

Australia

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ACTRN12605000796684