Assessment of latent left ventricular dysfunction in asymptomatic severe valvular regurgitation

This study is for people with severe mitral regurgitation — a condition where the mitral valve in the heart leaks blood backwards — who currently have no symptoms or only very mild symptoms. It is often unclear when to recommend heart surgery for people in this situation. The study is testing whether newer ultrasound (echocardiography) measurements can predict who is at risk of developing heart problems in the future, which would help doctors know when to act. You may be eligible if: - You have severe mitral regurgitation with no symptoms or only mild symptoms You may NOT be eligible if: - You have known coronary artery disease - You have had previous heart surgery - You have more than mild mitral stenosis (narrowing of the same valve) - You have significant aortic valve disease - Your heart ultrasound images are of poor quality Talk to your doctor about whether this trial might be right for you.