RecruitingPhase 2ACTRN12606000095561

“Sleep disturbances in subjects with asthma and rhinitis”

" A double blind, randomised, placebo controlled, cross-over, intervention study evaluating the effect of treating rhinitis in asthma with intranasal steroids to improve sleep.


Sponsor

The Woolcock Institute

Enrollment

30 participants

Start Date

Mar 10, 2006

Study Type

Interventional

Conditions

Summary

A majority of patients with asthma has nasal inflammation but it is not always diagnosed and treated. Nasal inflammation cause sleep disturbances that can be improved by treatment with nasal steroid spray. It has not been studied before if treatment with nasal steroids can improve sleep in patients with asthma. We will investigate 30 patients with asthma to see if their "quality of sleep" and "quality of life" can be improved by treament with nasal steroid spray compared to placebo.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 50 Yearss

Plain Language Summary

Simplified for easier understanding

This study is looking at whether a nasal steroid spray (a spray that reduces inflammation in your nose) can improve sleep quality in people who have asthma. Almost all asthma patients also have some nasal inflammation, even if they don't notice nasal symptoms. Poor sleep is common in asthma patients. This trial tests whether treating nasal inflammation helps people sleep better. You may be eligible if: - You are between 18 and 50 years old - You have a doctor-confirmed diagnosis of asthma You may NOT be eligible if: - You already use a nasal steroid spray that you cannot stop - You have a known diagnosis of obstructive sleep apnoea - You are taking oral steroid tablets - You were hospitalised for asthma in the last 12 months - Your inhaled steroid dose is very high (above 1000 mcg fluticasone or 1600 mcg budesonide per day) - You take sedatives or antipsychotic medications - You have nasal polyps, severely deviated nasal septum, or enlarged turbinates Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

6 weeks of intranasal Fluticasone spray 400 ug daily

6 weeks of intranasal Fluticasone spray 400 ug daily


Locations(1)

Australia

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ACTRN12606000095561