“Sleep disturbances in subjects with asthma and rhinitis”
" A double blind, randomised, placebo controlled, cross-over, intervention study evaluating the effect of treating rhinitis in asthma with intranasal steroids to improve sleep.
The Woolcock Institute
30 participants
Mar 10, 2006
Interventional
Conditions
Summary
A majority of patients with asthma has nasal inflammation but it is not always diagnosed and treated. Nasal inflammation cause sleep disturbances that can be improved by treatment with nasal steroid spray. It has not been studied before if treatment with nasal steroids can improve sleep in patients with asthma. We will investigate 30 patients with asthma to see if their "quality of sleep" and "quality of life" can be improved by treament with nasal steroid spray compared to placebo.
Eligibility
Exclusion Criteria1
- Pre-existing treatment with nasal steroids which is not able to be stoppedKnown obstructive sleep apnoea syndrome (OSAS)Treatment with oral steroidsPrevious hospitalisation (within the last 12 months) for asthmaInhaled steroid dosage exceeding 1000µg/day (fluticasone) or 1600ug/day (budesonide)Treatment with sedativesTreatment with neuroleptic pharamceuticalsNasal polypsSevere septal deviation or turbinate hypertrophy.
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Interventions
6 weeks of intranasal Fluticasone spray 400 ug daily
Locations(1)
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ACTRN12606000095561