CompletedPhase 3ACTRN12606000375550

The Benefits of Oxygen Saturation Targeting (BOOST) trial: different oxygen levels for preterm infants

A randomised trial of standard versus higher oxygen saturation levels on long term growth and development of infants

Sponsor

Centre for Perinatal Health Services Research, University of Sydney

Enrollment

358 participants

Start Date

Sep 15, 1996

Study Type

Interventional

Conditions

Preterm infants

Summary

The trial assessed the effect of different oxgen saturation targeting ranges on the long-term growth and development of oxygen-dependent, extremely preterm infants.

Eligibility

Sex: Both males and femalesMin Age: 24 WeekssMax Age: 29 Weekss

Plain Language Summary

Simplified for easier understanding

This study (the BOOST trial) compares different oxygen level targets for very premature babies who were born before 30 weeks and still need supplemental oxygen at 32 weeks. It aims to find the safest oxygen range to reduce lung and eye problems while supporting healthy development.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Targeting two different oxygen saturation target ranges, SpO2 (oxygen saturation) 91-94% (control) vs SpO2 95-98% (treatment), using pulse oximetry from 32 weeks postmentrual age for the duration of t

Locations(1)

Australia

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