Clinical efficacy of Moxifloxacin in the treatment of Bacterial Keratitis: A Randomised Clinical Trial

To determine clinical efficacy and safety for topical moxifloxacin (1.0%) in patients treated with bacterial keratitis. A comparison will be made to patients treated with topical ofloxacin (0.3%) or topical fortified tobramycin (1.33%)/cephazolin(5%). After corneal specimens are obtained, the assigned study medication is to be instilled every hour day and night for 48 hours and on the third day every hour by day and every two hours at night. For days four and five one drop every two hours by day and every four hours at night and for days six and seven one drop every four hours. After day seven, the antibiotic is to be tapered to six hourly and stopped when when the ulcer has healed.