RecruitingACTRN12607000050459

Chlorhexidine in preterm babies

Use of chlorhexidine as a topical antiseptic for the prevention of nosocomial sepsis in premature neonates < 29 weeks: a blinded randomised controlled trial


Sponsor

Sandie Bredemeyer

Enrollment

169 participants

Start Date

Apr 4, 2005

Study Type

Interventional

Conditions

Summary

Strategies for reducing infection are vital in caring for the premature neonate, and include, the use of a topical antiseptic for skin cleansing prior to any invasive procedure that compromises the skin barrier. There is currently little research addressing the issue of what antiseptic solution is best and safest for use in this vulnerable neonatal population. Consequently a wide range of solutions are utilised within the NICU setting


Eligibility

Sex: Both males and femalesMin Age: 0 DayssMax Age: 29 Weekss

Plain Language Summary

Simplified for easier understanding

This study is for very premature babies born before 29 weeks of pregnancy. It tests whether using the antiseptic chlorhexidine to clean a baby's skin before medical procedures (like inserting a drip or taking blood) is safe and effective. Premature babies have very fragile skin and are at high risk of infection, so finding the safest antiseptic is very important. The study will observe how the babies' skin responds to the antiseptic over time. You may be eligible if: - Your baby was born at less than 29 weeks of pregnancy - Your baby was born at or transferred to a participating hospital - You have given informed consent You may NOT be eligible if: - You as the parent do not give consent - Your baby was transferred from another hospital after birth - Your baby has a severe birth defect that is unlikely to allow survival Talk to your doctor about whether this trial might be right for you.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Aqueous chlorhexidine 0.5% (intervention group) applied topically. The solution is applied prior to each invasive procedure for both control and intervention groups.

Aqueous chlorhexidine 0.5% (intervention group) applied topically. The solution is applied prior to each invasive procedure for both control and intervention groups.


Locations(1)

Australia

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ACTRN12607000050459