RecruitingACTRN12607000050459

Chlorhexidine in preterm babies

Use of chlorhexidine as a topical antiseptic for the prevention of nosocomial sepsis in premature neonates < 29 weeks: a blinded randomised controlled trial


Sponsor

Sandie Bredemeyer

Enrollment

169 participants

Start Date

Apr 4, 2005

Study Type

Interventional

Conditions

Summary

Strategies for reducing infection are vital in caring for the premature neonate, and include, the use of a topical antiseptic for skin cleansing prior to any invasive procedure that compromises the skin barrier. There is currently little research addressing the issue of what antiseptic solution is best and safest for use in this vulnerable neonatal population. Consequently a wide range of solutions are utilised within the NICU setting


Eligibility

Sex: Both males and femalesMin Age: 0 DayssMax Age: 29 Weekss

Inclusion Criteria1

  • Inborn infants < 29 weeks. Informed parental consent.

Exclusion Criteria1

  • Parental consent not given. Ex utero transfer, unlikely to survive major congenital anomaly.

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Interventions

Aqueous chlorhexidine 0.5% (intervention group) applied topically. The solution is applied prior to each invasive procedure for both control and intervention groups.

Aqueous chlorhexidine 0.5% (intervention group) applied topically. The solution is applied prior to each invasive procedure for both control and intervention groups.


Locations(1)

Australia

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ACTRN12607000050459