The effect of skim milk products on serum uric acid levels
The effect of skim milk products on serum uric acid levels for the prevention of gout
LactoPharma Consortium
16 participants
Jun 14, 2007
Interventional
Conditions
Summary
Recent studies have identified ingestion of dairy products as protective for the development of gout. This effect is likely to be due to the uric acid lowering effect of factors within milk. The proposed study will analyse the effect of specific skim milk products on uric acid levels in healthy men, in an attempt to understand how dairy products influence uric acid levels. This is a cross-over pilot study of short term urate-lowering effects of skim milk powders. We will study 16 healthy male participants. Participants will attend four study visits, each lasting approximately four hours and on each visit will receive a milk product. Blood and urine samples will be taken over the four hour period. Participants will receive all four study products over an eight week period, but products will be administered in a random order.
Eligibility
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Interventions
This is a short term crossover study. Each participant will receive a single dose of each of the following products, each in a different order. Each product will be given orally at a standard dose of 80g protein in 800ml of water. Participants will attend four study visits, each at least one week apart, over an eight week period. The following products will be tested: Control agent: soy protein (Code number 06/8040/1668) Study agents: three skim milk products (Code numbers 01/7939/1274, 03/7939/1276, and 07/000/1275).
Locations(1)
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ACTRN12607000187448