Oxygen therapy in pneumonia

This study is for people who come to hospital with pneumonia (a lung infection). Standard treatment gives all pneumonia patients high-flow oxygen, but there is evidence this may not always be helpful and could even be harmful in some patients. This trial tests whether adjusting the amount of oxygen given based on the patient's actual blood oxygen levels (called titrated oxygen therapy) works as well as or better than the standard high-flow oxygen approach. You may be eligible if: - You are between 18 and 75 years old - You have a cough - You have at least one sign of infection such as sweating, shivering, or fever above 37.8°C - Your breathing rate is more than 18 breaths per minute You may NOT be eligible if: - You need a breathing machine (mechanical ventilation) - You have been diagnosed with COPD or emphysema - Your heart test (ECG) shows signs of a heart attack - You are suspected to have low white blood cell count with infection (neutropenic sepsis) - You have a known chronic breathing condition due to nerve or muscle disease, chest wall problems, or obesity Talk to your doctor about whether this trial might be right for you.