CompletedPhase 3Phase 4ACTRN12607000367448
The long term effect of inhaled hypertonic saline (6%) in non-cystic fibrosis bronchiectasis.
The long term effect of inhaled hypertonic saline (6%) on pulmonary exacerbations, quality of life and lung function in patients with non-cystic fibrosis bronchiectasis.
Sponsor
Alfred Hospital, Physiotherapy Department
Enrollment
40 participants
Start Date
Dec 20, 2007
Study Type
Interventional
Conditions
Summary
The main purpose of this study is to determine whether the long term inhalation of a salt solution will decrease the number of lung infections and improve the quality of life of people with bronchiectasis.
Eligibility
Sex: Both males and femalesMin Age: 18 Yearss
Inclusion Criteria1
- Diagnosis of bronchiectasis using high resolution computer tomography (HRCT), at least two pulmonary exacerbations over past year, producing sputum daily, stable clinical state
Exclusion Criteria1
- Cystic fibrosis, clinically unstable, unable to tolerate hypertonic saline (6%)
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Interventions
Hypertonic saline (6%) - 5mls nebulsied twice a day for 12 months
Hypertonic saline (6%) - 5mls nebulsied twice a day for 12 months
Locations(1)
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ACTRN12607000367448