CompletedPhase 3ACTRN12607000470493

Topical vapocoolant spray in reducing the pain of intravenous cannulation in the emergency department: a randomised, single-blinded, placebo-controlled trial

A randomised controlled clinical trial to compare the efficacy of pressurised vapocoolant and water sprays in decreasing the pain of intravenous cannulation in emergency department patients.


Sponsor

Austin Health

Enrollment

200 participants

Start Date

Oct 1, 2007

Study Type

Interventional

Conditions

Summary

Vapocollant spray is used overseas to decrease the pain of intravenous cannulation. However, no randomised controlled trial has been reported to provide evidence for this.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Inclusion Criteria1

  • Emergency department patients, aged 18 years or more, requiring intravenous cannulation.

Exclusion Criteria1

  • Refusal to provide consent; Inability to provide informed consent (Non-English speaking, altered mental state, significant illness); Moderate to severe discomfort or pain; Diseases of the skin associated with cold intolerance (eg: Raynaud’s phenomenon); Known allergy to spray contents; Peripheral neuropathy; Parenteral analgesia in the previous 4 hours

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Interventions

Two second spray of pressurised vapocoolant "COLD Spray" (butane, propane, pentane blend), from 12 cm, to the IV cannulation site. The alkane blend may vary with the batch and specific proportions of

Two second spray of pressurised vapocoolant "COLD Spray" (butane, propane, pentane blend), from 12 cm, to the IV cannulation site. The alkane blend may vary with the batch and specific proportions of the three alkanes are not available


Locations(1)

Australia

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ACTRN12607000470493