The protection of left ventricular function during right ventricular pacing.
PROTECT-PACE study: To assess the protection of left ventricular function during right ventricular pacing in patients diagnosed with complete heart block.
Medtronic Australasia
238 participants
Aug 1, 2007
Interventional
Conditions
Summary
For many years the standard approach to lead placement has been the right ventricular apex (RVA). However, early evidence suggests that right ventricular high septum (RVHS) pacing may be more beneficial compared to RVA pacing. Patients with complete heart block requiring more than 90% ventricular pacing will be randomised into two groups; RVA vs RVHS pacing. The two pacing modalities will be compared to assess left ventricular function as measured by the left ventricular ejection fraction.
Eligibility
Inclusion Criteria1
- Patients diagnosed with high-grade A-V block scheduled to undergo pacemaker implantation.
Exclusion Criteria1
- Patient with intermittent AV block or scheduled for Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy.
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Interventions
Implant of pacemaker and lead system. Results after a follow-up period of 24 months will be compared between right ventricular apex (RVA) vs right ventricular high septum (RVHS) lead placement. At the end of the study the treatment continues. Right ventricular apex: Area at the base of the right ventricle in the heart. Right ventricular high septum: Area near the top of the right ventricle closer to the middle of the heart.
Locations(2)
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ACTRN12607000479404