Measuring ovarian reserve in women having laparoscopic surgery.
Anti-Mullerian Hormone measurement as a measure of ovarian reserve in women having a unilateral ovarian cystectomy
WCH Foundation Grant
30 participants
Aug 10, 2007
Observational
Conditions
Summary
Informed consent obtained to take blood tests for AMH level estimation before surgery andat 2 time points afterwards
Eligibility
Inclusion Criteria3
- women with regular natural menstrual cycles or on COC contraceptive
- Women on the combined oral contraceptive can be included as recent data shows that AMH levels are not altered by the pill.
- women undergoing an laparoscopic gynaecological procedure.
Exclusion Criteria5
- women unable or unwilling to independently give informed consent to participate in this study.
- Women on medications that interfere with AMH levels.
- Women with polycystic ovarian syndrome (AMH levels are high)
- Women with malignant pathology.
- Women who are deemed unsuitable to participate in this study as assessed by their lead clinician.
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Interventions
Ovarian reserve is an estimate of the number of oocytes in the ovary. Anti-mullerian Hormone is thought to be one of the best measures of ovarian reserve. Despite this the assay is not widely available and Adelaide is the only city in Australia that provides this test mainly in a research setting. It is not routinely used to assess ovarian reserve after ovarian surgery. A blood test for Anti-mullerian hormone will be taken immediately prior to surgery then at 6 weeks and 3 months after surgery.
Locations(1)
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ACTRN12607000523404