chronOS Implant Evaluation Study. The Canberra Surgicentre and Synthes Australia are conducting a clinical study to evaluate the performance of chronOS granules (bone substitute) following the extraction of wisdom tooth/teeth to prevent the risk of periodontal defects.

This study is testing whether filling the socket left after a wisdom tooth (mandibular third molar) is removed with a synthetic bone substitute called chronOS can prevent a specific type of gum and bone problem that sometimes develops on the adjacent second molar. When wisdom teeth are removed — particularly in adults over 26 — a bony defect can form nearby, leading to a gum problem called a periodontal defect. This study will follow patients for at least 12 months after the procedure to see if chronOS reduces this risk. You may be eligible if: - You are 18 years of age or older - You are having both lower wisdom teeth removed - Your wisdom teeth are in a mesioangular or horizontal position (leaning forward) - You are willing to attend follow-up appointments for at least 12 months You may NOT be eligible if: - You are under 18 years of age - The tooth next to your wisdom tooth (second molar) is missing - You have diabetes - You are taking long-term steroid medications - You have had radiation therapy to the jaw - You have or have had a malignant condition Talk to your doctor about whether this trial might be right for you.