Effect of n-3 fatty acids on outcomes following hip fracture: a pilot study to investigate proof of concept, feasibility of recruitment and adherence to a 6 week fish oil intervention.
Inflammatory markers have been found to be raised in hip fracture patients. It is plausible that fish oils will counteract production of these chemicals and reduce weight and muscle loss which is experienced in many of these patients. This study will investigate proof of this concept, feasibility of recruitment and adherence to fish oil liquid or capsules.
Eligibility
Sex: Both males and femalesMin Age: 60 Yearss
Plain Language Summary
Simplified for easier understanding
This pilot study is investigating whether fish oil supplements — which are known to reduce inflammation — can help elderly patients who have just broken their hip recover better and lose less weight and muscle. Hip fractures are very common in older adults and are often followed by significant weight loss and weakness, which can delay recovery. Researchers will test whether fish oil can reduce the inflammation seen in these patients and whether it is practical to carry out a larger study.
You may be eligible if:
- You are 60 years of age or older
- You have recently suffered a hip fracture
- Your memory and thinking are intact (MMSE score above 24 out of 30)
- You are at risk of weight loss (based on an appetite questionnaire)
- Your blood inflammation marker (CRP) is elevated (6 mg/L or more)
You may NOT be eligible if:
- You have a known allergy to fish
- You have recently started anti-inflammatory corticosteroids (in the past 2 weeks)
- You have been taking omega-3 supplements in the past 4 weeks
- Your life expectancy is less than 6 weeks
Talk to your doctor about whether this trial might be right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
6 week fish oil intervention (15ml/day liquid fish oil (4.9g EPA) OR
9 fish oil capsules/day (4.8g EPA)
6 week fish oil intervention (15ml/day liquid fish oil (4.9g EPA) OR
9 fish oil capsules/day (4.8g EPA)
Locations(1)
Australia
View Full Details on ANZCTR
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