Fish oil and hip fracture
Effect of n-3 fatty acids on outcomes following hip fracture: a pilot study to investigate proof of concept, feasibility of recruitment and adherence to a 6 week fish oil intervention.
Dr Michelle Miller
30 participants
Mar 3, 2008
Interventional
Conditions
Summary
Inflammatory markers have been found to be raised in hip fracture patients. It is plausible that fish oils will counteract production of these chemicals and reduce weight and muscle loss which is experienced in many of these patients. This study will investigate proof of this concept, feasibility of recruitment and adherence to fish oil liquid or capsules.
Eligibility
Inclusion Criteria6
- years or over
- Hip fracture sufferers
- No cognitive impairment according to the Mini Mental State Examination (MMSE score over 24/30)
- At risk of subsequent weight loss according to the Simplified Nutrition Appetite Questionnaire (SNAQ score less than or =14/20)
- Elevated CRP (6mg/L or more)
- Able to consent
Exclusion Criteria4
- Allergy to fish
- Initiation of anti-inflammatory corticosteroids within the prior two weeks
- Ingestion of n-3 fatty acid supplements within four weeks of study initiation
- Life expectancy less than 6 weeks
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Interventions
6 week fish oil intervention (15ml/day liquid fish oil (4.9g EPA) OR 9 fish oil capsules/day (4.8g EPA)
Locations(1)
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ACTRN12608000099325