Comparison of triple phase and lipid only intra-dialytic parenteral nutrition and survival and outcomes in malnourished haemodialysis patients to assess complications.
Randomised blinded trial to compare triple phase and lipid only intra-dialytic parenteral nutrition in malnourished haemodialysis patients to assess survival, complications and improvements in nutrition.
Austin Health
30 participants
Aug 1, 2008
Interventional
Conditions
Summary
Several formulations have been used for IDPN and have ranged from those with minimal provision of nutrients to those that deliver significant amounts of calories and amino acids. Administration of lipid was originally considered to be contraindicated in IDPN but studies suggest otherwise and lipids are now used routinely. Austin Health is the first dialysis centre in the world to use standard lipid only IDPN solution. Since then a 20% lipid 500 ml or 30% lipid 250 ml solutions are routinely used in our haemodialysis patients requiring IDPN support. What effect if any is this practice having? Would the use of a more standardised practice of protein, lipid and dextrose combined solution be more beneficial?
Eligibility
Plain Language Summary
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Interventions
Malnourished haemodialysis patients will be randomised to 1000kcal 20% lipid ClinOleic Intra-Dialytic Parenteral Nutrition (IDPN) solution given via the dialysis line during the dialysis session 3 x week for up to 3 months.
Locations(1)
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ACTRN12608000123347