RecruitingACTRN12608000142336

Acute alerting effects of daytime exposure to specific wavelengths of light

The effectiveness of exposure to different colours of light in improving alertness and psychomotor vigilance in sleep restricted and non-sleep restricted healthy adult participants

Sponsor

Monash University

Enrollment

120 participants

Start Date

Jan 21, 2008

Study Type

Interventional

Conditions

Primary health condition: Alertness and psychomotor vigilance in healthy human volunteers.

Summary

This study examines the effects of different colours of light on sleepiness and performance on various tasks. It is predicted that exposure to blue light will reduce sleepiness and improve performance more effectively than other colours of light.

Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 30 Yearss

Inclusion Criteria2

(1) Male and female adults aged 18 to 30 years inclusive
(2) Healthy

Exclusion Criteria13

(1) Individuals who have engaged in shiftwork/nightwork in the past 3 years and/or transmeridian travel in the past 3 months.
(2) Individuals who smoke, report high caffeine intake and/or high alcohol consumption.
(3) Individuals who screen positive for drugs of abuse following comprehensive urine toxicological analysis.
(4) Women who are pregnant, lactating or planning to become pregnant during the study period.
(5) A history of alcohol/drug dependence.
(6) Current, recent (<3 months) or chronic history of use of drugs or medication that affect the central nervous system (except non-steroid topical creams, oral contraceptives and occasional use of mild pain killers.
(7) History of psychiatric illness.
(8) Recent acute or chronic medical illness.
(9) Abnormal sleep patterns/sleep disorders.
(10) Auditory defects.
(11) Any form of photophobia including drug-induced, epilepsy, seizures, vertigo or migraine.
(12) Individuals with diseases of the visual system.
(13) Females who are not taking a medically approved form of birth control.

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Interventions

Intervention: Ocular exposure to specific monochromatic wavelengths of light administered using a specialised light delivery system. For three hours, each participant will be exposed to one of the f

Intervention: Ocular exposure to specific monochromatic wavelengths of light administered using a specialised light delivery system. For three hours, each participant will be exposed to one of the following wavelengths of light: violet light (420nm), blue light (460nm), green light (555nm), or red light (620nm).

Locations(1)

Australia

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ACTRN12608000142336