RecruitingPhase 3Phase 4ACTRN12608000181303

Detection of recombinant human luteinising hormone (rLH) as a doping agent

Detection of recombinant human luteinising hormone as a doping agent in healthy male volunteers aged 18 to 45. An open label, randomised clinical study.


Sponsor

Sydney South Western Area Health Service (SSWAHS)

Enrollment

64 participants

Start Date

Nov 23, 2004

Study Type

Interventional

Conditions

Summary

Sports anti-doping study


Eligibility

Sex: MalesMin Age: 18 YearssMax Age: 45 Yearss

Inclusion Criteria1

  • Healthy males

Exclusion Criteria1

  • No recent history of steriod use

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Interventions

Half of the participants will have a 200mg injection of Nandrolone decanoate, then 3 days later a single dose of rLH 75IU or 225IU or recombinant human chorionic gonadotropin 'rhCG' 250ug or 750ug .

Half of the participants will have a 200mg injection of Nandrolone decanoate, then 3 days later a single dose of rLH 75IU or 225IU or recombinant human chorionic gonadotropin 'rhCG' 250ug or 750ug . Those given 'rhCG' will have another 100mg dose of Nandrolone decanoate the following day. The other half of the participants will be given either a single dose of either rLH 75IU or 225IU or rhCG 250ug or 750ug without the Nandrolone. Blood and urine samples will be obtained at intervals form 0 for up to 8 days.


Locations(1)

Australia

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