Not Yet RecruitingPhase 2ACTRN12608000297325
The Analgesic Efficacy of Ultrasound-Guided Transversus Abdominis Plane Blocks after Abdominal Surgery
The Analgesic Efficacy of Ultrasound Guided Transversus Abdominis Plane (TAP) blocks compared with Placebo in Patients Undergoing Abdominal Surgery
Sponsor
Dr Elizabeth Hessian
Enrollment
52 participants
Start Date
Feb 1, 2009
Study Type
Interventional
Conditions
Summary
This trial is looking at the analgesic efficacy of transversus abdominis plane block (TAP block) using ropivacaine following abdominal surgery.
Eligibility
Sex: Both males and femalesMin Age: 18 Yearss
Inclusion Criteria2
- Age over 18 years
- Elective or semi-elective abdominal surgery requiring mid-line incision
Exclusion Criteria10
- Patient refusal
- Acute abdomen
- A clinical history consistent with opioid tolerance including preoperative opioid consumption of longer than one week, intravenous opioid drug use
- Preoperative use of opioid antagonists like buprenorphine and naltrexone
- A clinical history of chronic pain, where patients may benefit from early commencement of agents like ketamine
- Renal impairment with creatinine clearance less than 60 mL/min
- Drug allergy or contraindication to morphine, ropivacaine, paracetamol
- Anaesthetist preference for placement of central neuroaxial blockade/catheter
- Surgeon refusal to placement of catheters
- Inability of patient to use patient controlled analgesia pump post-operatively or to understand grading of pain via verbal pain score
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Interventions
Transversus abdominis plane injection using ropivacaine 0.5%, 20ml bilaterally at the completion of surgery prior to waking from anaesthesia
Transversus abdominis plane injection using ropivacaine 0.5%, 20ml bilaterally at the completion of surgery prior to waking from anaesthesia
Locations(1)
View Full Details on ANZCTR
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ACTRN12608000297325