RecruitingACTRN12608000450314

The Protein StudyThe effect of protein intake on circulating inflammatory markers in women with obesity

The effect of protein intake on circulating inflammatory markers in women with obesity


Sponsor

University of Otago

Enrollment

25 participants

Start Date

Jul 15, 2008

Study Type

Interventional

Conditions

Summary

Pro-inflammatory cytokines concentrations are elevated in the fasting and postprandial state and are thought to contribute to the high risk of insulin resistance and type 2 diabetes in obesity. Ingestion of protein and especially dairy protein, increases the secretion of insulin that has anti-inflammatory activity. The study aims to determine whether ingestion of dairy protein with or without carbohydrate decreases postprandial levels of pro-inflammatory cytokines in obese women. The findings will be highly relevant to the use of high -protein diets in the management of obesity and type 2 diabetes.


Eligibility

Sex: FemalesMin Age: 30 YearssMax Age: 70 Yearss

Plain Language Summary

Simplified for easier understanding

This study is looking at how eating dairy protein (like milk protein) affects inflammation in the body in obese women. Being overweight can raise inflammation levels in the blood, which is linked to a higher risk of insulin resistance and type 2 diabetes. Dairy protein causes the body to release insulin, which may actually reduce this inflammation. Researchers will measure inflammation markers in the blood after women eat different protein and carbohydrate meals to see if dairy protein can help. You may be eligible if: - You are a woman between 30 and 70 years of age - You have a BMI (Body Mass Index) over 30 - Your waist measurement is greater than 88 cm (about 35 inches) You may NOT be eligible if: - You currently smoke cigarettes - You have cardiovascular (heart) disease - You have active infections or other serious medical conditions - You are taking certain medications that would interfere with the study Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

All participants consume 2 protein meals consisting of 19.5gms of dairy protein per meal. The meals are consumed on 2 different occasions with an interval of at least 1 week between the meals.

All participants consume 2 protein meals consisting of 19.5gms of dairy protein per meal. The meals are consumed on 2 different occasions with an interval of at least 1 week between the meals.


Locations(1)

Otago, New Zealand

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12608000450314