CompletedPhase 2ACTRN12608000558325

A Pilot Efficacy and Safety Study of IPX159 for the Treament of Restless Legs Syndrome.


Sponsor

IMPAX Pharmaceuticals

Enrollment

28 participants

Start Date

Feb 12, 2009

Study Type

Interventional

Conditions

Summary

The primary purpose of this Study is to find out if a new medication can help people that suffer from Restless Leg Syndrome. Over the course of 7 weeks, several assessments will be made to see how a person with restless leg syndrome sleeps and whether or not this medication can reduce their discomfort and therefore improve their quality of life.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests a new medication called IPX159 for people with moderate to severe Restless Legs Syndrome, a condition that causes uncomfortable urges to move the legs, especially at night. Participants must be at least 18 years old and have documented symptoms on at least 10 nights per month. People with certain other sleep disorders, mental health conditions, diabetes, or who are pregnant cannot take part.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

This is a crossover study with 2 treatment: A. placebo taken orally 3 times a day. B. 30 escalating to 60mg IPX159 taken orally 3 times a day. Patients will be randomised and will have each treatme

This is a crossover study with 2 treatment: A. placebo taken orally 3 times a day. B. 30 escalating to 60mg IPX159 taken orally 3 times a day. Patients will be randomised and will have each treatment for 3 weeks. Patients will be exposed to treatment for 3 weeks over a 7-week period. The wash-out period between the 2 treatment arms is 1 week. During the treatment period, Patients will take 1 tablet 3 times a day for the first 2 days, then at day 3, the dose is increased to 2 tablets 3 times a day. If patients can not tolerate the dose increase, they can decrease the dose back down to 1 tablet 3 times a day.


Locations(1)

NSW,QLD,VIC, Australia

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