A Phase II, Double Blind, Placebo-controlled, Randomized, Multi-Center, Parallel Group Study to Evaluate The Efficacy and Safety of T89, drug name: Dantonic 'Registered trade mark' in Patients with Chronic Stable Angina Pectoris
A Phase II, Study to Evaluate The Efficacy and Safety of Dantonic 'Registered trade mark' in Patients with Chronic Stable Angina Pectoris
CNS Pty Ltd
70 participants
Jun 12, 2008
Interventional
Conditions
Summary
This is a phase II clinical trial that will use double blind, placebo-controlled, randomized, multi-center, parallel group study design to evaluate the efficacy and safety of T89 in patients with chronic stable angina pectoris.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
This prospective, double-blind, randomized, multi-center, and placebo-controlled, 2 parallel group phase II trial is to investigate the anti-angina effect of T89 at 187.5 mg, administered orally every 12 hours (daily dose 375 mg) for 8 weeks, while all other concurrent medications for angina pectoris are discontinued except short-acting nitrates (taken as required by patient), beta-blockers or calcium channel blockers, in its ability to enhance exercise tolerance in patients with chronic stable angina pectoris. Exercise Tolerance Tests (ETTs), Safety checks and frequency of Angina.
Locations(1)
View Full Details on ANZCTR
For the most up-to-date information, visit the official listing.
ACTRN12609000044224