Not Yet RecruitingPhase 4ACTRN12609000066280

Investigation of Caspofungin Eye Drops for the Treatment of Fungal Eye Infections

Ocular Penetration of Caspofungin Eye Drops in the Treatment of Fungal Keratitis

Sponsor

Monash

Enrollment

30 participants

Start Date

Apr 1, 2009

Study Type

Interventional

Conditions

Fungal Keratitis

Summary

This proposed study is intended to investigate if the antifungal drug, caspofungin, when applied as an eye drop is able to penetrate into the human eyes. The use of caspofungin as an eye drops in human has never been reported. Caspofungin eye drops are anticipated to safely penetrate into the human eyes when applied as eye drops and to achieve adequate concentrations to treat fungal eye infections.

Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study investigates whether caspofungin, an antifungal medication, can be safely used as eye drops to treat fungal eye infections. It is for adults aged 18 and older who are attending hospital for planned eye surgery such as cataract surgery. Participation involves receiving the eye drops and being monitored for safety.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

One drop of 0.5% Caspofungin eye drops will be administered hourly into the eye that will be operated on (commencing 4 hours before participant's elective surgery).

Locations(1)

Australia

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ACTRN12609000066280

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