ActivePhase 2Phase 3ACTRN12609000111279

The effects of memantine versus placebo on visual functions after scleral buckling for regmatogenous retinal detachment (RRD)

The effects of memantine versus placebo on visual acuity , optical coherence tomogapy (OCT) , contrast sensitivity , multifocal electroretinography (mERG) after scleral buckling for regmatogenous retinal detachment (RRD)

Sponsor

Tehran University of Medical sciences

Enrollment

60 participants

Start Date

Feb 20, 2008

Study Type

Interventional

Conditions

patients with rhegmatogenus retinal detachment undergoing scleral buckeling surgery

Summary

Evaluation of the neuroprotective effect of Memantine in visual function of patients with macula off RRD of less than 1 months duration. Our hypothesis was that Memantine helps for better improvement of visual function in these patientsafter successful scleral buckling.

Eligibility

Sex: Both males and femalesMin Age: 20 Yearss

Plain Language Summary

Simplified for easier understanding

This trial tests whether the medication memantine can help improve vision after surgery for a detached retina. It is for adults aged 20 and older who have recently had their retina detach and need surgery to repair it. Participants will receive either memantine or a placebo pill after their surgery, and their vision will be monitored over time.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

intervention: Memantine tablets for treatment group for 3 weeks orally(5mg/day for the first week and 10 mg/ day for the next two weeks)

Locations(1)

Iran, Islamic Republic Of

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ACTRN12609000111279