CompletedPhase 2ACTRN12609000163202

A randomised phase IIb, placebo controlled trial to assess the efficacy and safety of ReCharge (a medical food) in preventing chemotherapy induced diarrhoea (CID) when administered daily to patients undergoing chemotherapy.


Sponsor

Fonterra Co-operative Group Limited

Enrollment

200 participants

Start Date

Aug 3, 2009

Study Type

Interventional

Conditions

Summary

ReCharge is a food supplement which contains two milk bioactive components, milk fat and lactoferrin. The purpose of this study is to test the effectiveness of ReCharge in preventing chemotherapy induced diarrhoea (CID). To find out if ReCharge works this study compares ReCharge ice cream (the study product) with an inactive ice cream product (called a placebo). The inactive ice cream looks and tastes just like the ReCharge icecream. Participants will be allocated to one of these two products with equal chances of each product being the one received. Neither the participants nor doctors will know which product participants will be receiving. During the study participants will complete a daily gastrointestinal symptom diary and Quality of Life questionnaire and dietary habits questionnaire at study visits.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This trial tests whether a special medical food product (ReCharge, an ice cream-based product) can prevent diarrhea caused by chemotherapy. It is for adults aged 18 and over who are starting a new cycle of chemotherapy known to cause diarrhea. Participants eat the study product daily during their chemotherapy cycle.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Each patient is expected to ingest a single 100g tub of the investigational product (ReCharge) per day for a total of 8 weeks, starting 2 weeks +/- 4 days before chemotherapy and continuing for the fi

Each patient is expected to ingest a single 100g tub of the investigational product (ReCharge) per day for a total of 8 weeks, starting 2 weeks +/- 4 days before chemotherapy and continuing for the first 6 weeks of chemotherapy. ReCharge icecream is a medical food which contains two milk bioactive components, milk fat and lactoferrin.


Locations(1)

New Zealand

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ACTRN12609000163202