CompletedPhase 4ACTRN12609000290291

A comparison of oral prednisolone and oral dexamethasone in children with croup: a prospective, randomised, double blinded multicentre trial

Oral Prednisolone vs oral Dexamethasone (in two different doses) in children with croup: Randomised Clinical Trial comparing the improvement in Westley Croup Score.

Sponsor

Dr Colin Parker

Enrollment

1,400 participants

Start Date

Mar 27, 2009

Study Type

Interventional

Conditions

Croup (laryngotracheitis, laryngotracheobronchitis)

Summary

This clinical trial is designed to test whether the three commonly used oral steroid treatment regimes for croup, are equally effective. Children will receive one of the three treatments, decided by a random process, and their improvement and outcomes monitored by investigators who are blinded to the treatment received.

Eligibility

Sex: Both males and femalesMin Age: 6 MonthssMax Age: 10 Yearss

Plain Language Summary

Simplified for easier understanding

This study compares two steroid medications — prednisolone and dexamethasone — given by mouth to children aged 6 months to 10 years (weighing up to 20 kg) with croup, a common childhood condition causing a barking cough and breathing difficulty. The study aims to find which medication works better for symptom relief.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Group 1 - oral prednisolone 1 mg/kg oral liquid, single dose; Group 2 - oral dexamethasone 0.15 mg/kg oral liquid, single dose;

Locations(1)

Australia

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ACTRN12609000290291